Although Mohamed Hefzy studied Metallurgical engineering in London, and still works part time managing his family's copper manufacturing business, he has already, within 15 years, established himself among the Arab world's most successful screenwriters and producers. In 2013, he was the only Arab to be selected by Screen International magazine as one of the future leaders in the field of film production worldwide.
His earlier films as a Screenwriter include the hits El Selem Wi El Te’ban (Snake and Ladder) (2001), Tito (2004), Malaki Eskenderia (Private Alexandria) (2005), which earned him the Best Screenwriter Award from the Egyptian Catholic Center Cinema Festival, 45 Youm (45 Days) (2007), for which he received the Best Screenwriter Award at the Egyptian Oscars, and El Tourbini (2007). His latest writing credits include From A to B (2014), Warda (2014), the first Egyptian feature created in the Found Footage style in the Arab world, and Aswar Al Aamar (2015).
In 2005, he founded Film Clinic as a development and production company, and in 10 years, he had already produced and co-produced 30 feature films and TV productions in Egypt, the US, the UK and the Arab world.
In addition to writing and producing, Hefzy has played an important role in film distribution too. In 2016, he founded Film Clinic-Indie Distribution (FCID), which distributed the films Ali, the Goat and Ibrahim by Sherif El Bendary, Withered Green by Mohammed Hammad and Barakah Meets Barakah by Mahmoud Sabbagh.
Hefzy is an active participant and speaker at several regional and international festivals, the last of which was at the Berlinale 2017 and Dubai International Film Festival (DIFF) in 2016. He was also a jury member at the 2010 Cairo International Film Festival (CIFF) and Abu Dhabi Film Festival in 2012. Hefzy has joined the Board of Directors of the Egyptian Chamber of Cinema Industry in September, 2013, as a representative of the new independent cinema. He was also appointed as the Festival Director of the 16th Ismailia International Film Festival for Documentaries and Shorts. For his artistic contribution in uplifting and supporting independent filmmaking in Egypt, Hefzy was honored at the 2nd Independent Arts Season in 2014. Hefzy was on the Advisory Board of CIFF for the Cairo Film Connection (CFC). In March 2018, the Minister of Culture, Ines Abdel-Dayem, announced that Hefzy has been selected as the President of the 40th Cairo International Film Festival (CIFF).
Hefzy has delivered lectures on screenwriting and moderated several workshops at the American University in Cairo (AUC), and also through Film Clinic, including the Virtual Cloud Filmmaking Salon Workshop, which was supported by the AUC, with the aim of empowering young filmmakers to make their films by using easily available mobile devices and internet technology. He organized a screenwriting workshop, through Film Clinic, led by famous American screenwriter Syd Field in July 2008. In 2017, Hefzy conducted an open seminar entitled ‘Creative Production and Alternative Distribution’ at the Greek Campus - The American University in Cairo (AUC). The seminar was organized by Film Clinic, in collaboration with Film Independent, the Arab Film Institute and the US Embassy in Cairo. Mohamed Hefzy conducted several workshops in producing, screenwriting and distribution, not only in Egypt, but also throughout the Arab world in many countries such as Jordan, Kuwait, and Qatar.
As a producer, Hefzy's films have gained wide international acclaim at several prestigious film festivals, including:
- Microphone (2010): An official selection at the Toronto International Film Festival and received three awards from the Cairo International Film Festival, Dubai International Film Festival and Carthage Film Festival in Tunisia.
- Asmaa (2011): Since its release, the film has successfully garnered 19 awards from regional and international film festivals.
- 18 Days (2011): An official selection at the Cannes Film Festival 2011.
- Tahrir (2011): The Good, The Bad, and The Politician: A documentary that premiered at the Venice Film Festival and won Mohamed Hefzy the Best Arab Producer award (Documentary Competition) for at the Abu Dhabi Film Festival.
- My Brother the Devil (2012): Won two awards at the London Film Festival and the Sundance Film Festival.
- Asham (2013): Won two awards at the Malmo Arab Film Festival in Sweden and a Special Mention from the International Oriental Film Festival in Geneva.
- Rags and Tatters (2013): Won the Golden Antigone at the Montpellier Film Festival, made its world premiere at the Toronto International Film Festival and participated in the BFI London Film Festival as the only Arab film competing in the official competition.
- Villa 96 (2013): Received the Special Jury Award for a Film from the Arab World at the Abu Dhabi Film Festival, where it had its world premiere.
- Excuse My French (2014): Had its world premiere at the opening gala of the 2nd Luxor Egyptian and European Film Festival.
- From A to B (2014): Had its world premiere at the 8th Abu Dhabi Film Festival and was the festival opener.
- The Idol (2015): Won the Audience Award at the Dubai International Film Festival
- Al Madina (2015): World Premiere at the Dubai International Film Festival in the Official Competition.
- The Curve (2015): World Premiere at the Dubai International Film Festival in the Official Competition.
- Clash (2016): World Premiere at the Cannes Film Festival (opened the Un Certain Regard section) and Egypt’s official submission to the 2017 Academy Awards for Best Foreign Language Film.
- Hepta: The Last Lecture (2016): The highest-grossing romantic film in the history of Egyptian cinema.
- Withered Green (2016): Won the Best Director Award at the Dubai International Film Festival.
- Ali, the Goat and Ibrahim (2016): Won more than eight awards including the Best Actor Award (Ali Sobhi) at the Dubai International Film Festival.
- Sheikh Jackson (2017): Won two awards at the Egyptian Cinema Film Association Festival and one award at Mediterranean Film Festival of Annaba (FAFM). Egypt's official submission to the Academy Award for Best Foreign-Language Film 2018. World premiered at the 42nd Toronto International Film Festival within the Special Presentations programme.
- Gunshot (2018): The film was selected to participate in the Málaga Work In Progress held as part of the Málaga Film Festival in Spain.
- Yomeddine (2018): The film screened at the 2018 Cannes Film Festival in its official competition. Director Abu Bakr Shawky's feature film directorial debut is the first Egyptian film to participate in the festival's official competition after six years.
- Sawah (2018): Supported by Filmfund Luxembourg, the film wrapped shooting in April 2018.